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Design, Synthesis and Structure-Activity Relationships of Novel Chalcone-1,2,3-triazole-azole Derivates as Antiproliferative Agents

A series of novel chalcone-1,2,3-triazole-azole hybrids were designed, synthesized and evaluated for their antiproliferative activity against three selected cancer cell lines (SK-N-SH, EC-109 and MGC-803). Most of the synthesized compounds exhibited moderate to good activity against all the cancer c...

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Detalles Bibliográficos
Autores principales: Zhang, Sai-Yang, Fu, Dong-Jun, Yue, Xiao-Xin, Liu, Ying-Chao, Song, Jian, Sun, Hui-Hui, Liu, Hong-Min, Zhang, Yan-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274517/
https://www.ncbi.nlm.nih.gov/pubmed/27213317
http://dx.doi.org/10.3390/molecules21050653