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Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in Mixtures

Recent approaches in natural product (NP) research are leading toward the discovery of bioactive chemical entities at the microgram level. In comparison to classical large scale bioassay-guided fractionation, the use of LC-MS metabolite profiling in combination with microfractionation for both bioac...

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Detalles Bibliográficos
Autores principales: Bertrand, Samuel, Azzollini, Antonio, Nievergelt, Andreas, Boccard, Julien, Rudaz, Serge, Cuendet, Muriel, Wolfender, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274519/
https://www.ncbi.nlm.nih.gov/pubmed/26927035
http://dx.doi.org/10.3390/molecules21030259