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Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in Mixtures
Recent approaches in natural product (NP) research are leading toward the discovery of bioactive chemical entities at the microgram level. In comparison to classical large scale bioassay-guided fractionation, the use of LC-MS metabolite profiling in combination with microfractionation for both bioac...
Autores principales: | Bertrand, Samuel, Azzollini, Antonio, Nievergelt, Andreas, Boccard, Julien, Rudaz, Serge, Cuendet, Muriel, Wolfender, Jean-Luc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274519/ https://www.ncbi.nlm.nih.gov/pubmed/26927035 http://dx.doi.org/10.3390/molecules21030259 |
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