Computational Approaches for the Discovery of Human Proteasome Inhibitors: An Overview

Proteasome emerged as an important target in recent pharmacological research due to its pivotal role in degrading proteins in the cytoplasm and nucleus of eukaryotic cells, regulating a wide variety of cellular pathways, including cell growth and proliferation, apoptosis, DNA repair, transcription,...

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Detalles Bibliográficos
Autores principales: Guedes, Romina A., Serra, Patrícia, Salvador, Jorge A. R., Guedes, Rita C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274525/
https://www.ncbi.nlm.nih.gov/pubmed/27438821
http://dx.doi.org/10.3390/molecules21070927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274525/
https://www.ncbi.nlm.nih.gov/pubmed/27438821
http://dx.doi.org/10.3390/molecules21070927

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