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Computational Approaches for the Discovery of Human Proteasome Inhibitors: An Overview
Proteasome emerged as an important target in recent pharmacological research due to its pivotal role in degrading proteins in the cytoplasm and nucleus of eukaryotic cells, regulating a wide variety of cellular pathways, including cell growth and proliferation, apoptosis, DNA repair, transcription,...
Autores principales: | Guedes, Romina A., Serra, Patrícia, Salvador, Jorge A. R., Guedes, Rita C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274525/ https://www.ncbi.nlm.nih.gov/pubmed/27438821 http://dx.doi.org/10.3390/molecules21070927 |
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