Modulation of Autophagy by a Thioxanthone Decreases the Viability of Melanoma Cells

(1) Background: Our previous studies unveiled the hit thioxanthone TXA1 as an inhibitor of P-glycoprotein (drug efflux pump) and of human tumor cells growth, namely of melanoma cells. Since TXA1 is structurally similar to lucanthone (an autophagy inhibitor and apoptosis inducer) and to N(10)-substit...

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Detalles Bibliográficos
Autores principales: Lima, Raquel T., Sousa, Diana, Paiva, Ana M., Palmeira, Andreia, Barbosa, João, Pedro, Madalena, Pinto, Madalena M., Sousa, Emília, Vasconcelos, M. Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274546/
https://www.ncbi.nlm.nih.gov/pubmed/27735867
http://dx.doi.org/10.3390/molecules21101343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274546/
https://www.ncbi.nlm.nih.gov/pubmed/27735867
http://dx.doi.org/10.3390/molecules21101343

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