Improvement of Transmembrane Transport Mechanism Study of Imperatorin on P-Glycoprotein-Mediated Drug Transport

P-glycoprotein (P-gp) affects the transport of many drugs; including puerarin and vincristine. Our previous study demonstrated that imperatorin increased the intestinal absorption of puerarin and vincristine by inhibiting P-gp-mediated drug efflux. However; the underlying mechanism was not known. Th...

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Detalles Bibliográficos
Autores principales: Liao, Zheng-Gen, Tang, Tao, Guan, Xue-Jing, Dong, Wei, Zhang, Jing, Zhao, Guo-Wei, Yang, Ming, Liang, Xin-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274566/
https://www.ncbi.nlm.nih.gov/pubmed/27886150
http://dx.doi.org/10.3390/molecules21121606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274566/
https://www.ncbi.nlm.nih.gov/pubmed/27886150
http://dx.doi.org/10.3390/molecules21121606

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