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Structures of the human pre-catalytic spliceosome and its precursor spliceosome
The pre-catalytic spliceosome (B complex) is preceded by its precursor spliceosome (pre-B complex) and followed by the activated spliceosome (B(act) complex). The pre-B-to-B and B-to-B(act) transitions are driven by the ATPase/helicases Prp28 and Brr2, respectively. In this study, we report the cryo...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274647/ https://www.ncbi.nlm.nih.gov/pubmed/30315277 http://dx.doi.org/10.1038/s41422-018-0094-7 |