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Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis 

Iron has been shown to trigger oxidative stress by elevating reactive oxygen species (ROS) and to participate in different modes of cell death, such as ferroptosis, apoptosis and necroptosis. However, whether iron-elevated ROS is also linked to pyroptosis has not been reported. Here, we demonstrate...

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Detalles Bibliográficos
Autores principales: Zhou, Bo, Zhang, Jia-yuan, Liu, Xian-shuo, Chen, Hang-zi, Ai, Yuan-li, Cheng, Kang, Sun, Ru-yue, Zhou, Dawang, Han, Jiahuai, Wu, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274649/
https://www.ncbi.nlm.nih.gov/pubmed/30287942
http://dx.doi.org/10.1038/s41422-018-0090-y