Cargando…
Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis
Iron has been shown to trigger oxidative stress by elevating reactive oxygen species (ROS) and to participate in different modes of cell death, such as ferroptosis, apoptosis and necroptosis. However, whether iron-elevated ROS is also linked to pyroptosis has not been reported. Here, we demonstrate...
Autores principales: | Zhou, Bo, Zhang, Jia-yuan, Liu, Xian-shuo, Chen, Hang-zi, Ai, Yuan-li, Cheng, Kang, Sun, Ru-yue, Zhou, Dawang, Han, Jiahuai, Wu, Qiao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274649/ https://www.ncbi.nlm.nih.gov/pubmed/30287942 http://dx.doi.org/10.1038/s41422-018-0090-y |
Ejemplares similares
-
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8
por: Zhang, Jia-yuan, et al.
Publicado: (2021) -
Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors
por: Su, Jiayue, et al.
Publicado: (2022) -
Iron induces B cell pyroptosis through Tom20–Bax–caspase–gasdermin E signaling to promote inflammation post-spinal cord injury
por: Wu, Chengjie, et al.
Publicado: (2023) -
Two conformations of the Tom20 preprotein receptor in the TOM holo complex
por: Ornelas, Pamela, et al.
Publicado: (2023) -
The receptor subunit Tom20 is dynamically associated with the TOM complex in mitochondria of human cells
por: Bhagawati, Maniraj, et al.
Publicado: (2021)