Dexamethasone Inhibits Synergistic Induction of PDE4B Expression by Roflumilast and Bacterium NTHi

Phosphodiesterase 4B (PDE4B) plays an important role in inflammation. Recently we have reported that roflumilast as a PDE4-selective inhibitor, synergizes with nontypeable Haemophilus influenzae (NTHi) to up-regulate PDE4B expression in vitro and in vivo. Clinical evidence and our previous results s...

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Detalles Bibliográficos
Autores principales: Lee, Byung-Cheol, Susuki-Miyata, Seiko, Yan, Chen, Li, Jian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274694/
https://www.ncbi.nlm.nih.gov/pubmed/30413022
http://dx.doi.org/10.3390/ijms19113511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274694/
https://www.ncbi.nlm.nih.gov/pubmed/30413022
http://dx.doi.org/10.3390/ijms19113511

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