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Dexamethasone Inhibits Synergistic Induction of PDE4B Expression by Roflumilast and Bacterium NTHi
Phosphodiesterase 4B (PDE4B) plays an important role in inflammation. Recently we have reported that roflumilast as a PDE4-selective inhibitor, synergizes with nontypeable Haemophilus influenzae (NTHi) to up-regulate PDE4B expression in vitro and in vivo. Clinical evidence and our previous results s...
Autores principales: | Lee, Byung-Cheol, Susuki-Miyata, Seiko, Yan, Chen, Li, Jian-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274694/ https://www.ncbi.nlm.nih.gov/pubmed/30413022 http://dx.doi.org/10.3390/ijms19113511 |
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