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Dexamethasone Inhibits Synergistic Induction of PDE4B Expression by Roflumilast and Bacterium NTHi

Phosphodiesterase 4B (PDE4B) plays an important role in inflammation. Recently we have reported that roflumilast as a PDE4-selective inhibitor, synergizes with nontypeable Haemophilus influenzae (NTHi) to up-regulate PDE4B expression in vitro and in vivo. Clinical evidence and our previous results s...

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Detalles Bibliográficos
Autores principales:	Lee, Byung-Cheol, Susuki-Miyata, Seiko, Yan, Chen, Li, Jian-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274694/ https://www.ncbi.nlm.nih.gov/pubmed/30413022 http://dx.doi.org/10.3390/ijms19113511

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