Discovery of Novel Druggable Sites on Zika Virus NS3 Helicase Using X-ray Crystallography-Based Fragment Screening

The flavivirus family contains several important human pathogens, such as Zika virus (ZIKV), dengue, West Nile, and Yellow Fever viruses, that collectively lead to a large, global disease burden. Currently, there are no approved medicines that can target these viruses. The sudden outbreak of ZIKV in...

Descripción completa

Detalles Bibliográficos
Autores principales: Munawar, Ali, Beelen, Steven, Munawar, Ahmad, Lescrinier, Eveline, Strelkov, Sergei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274715/
https://www.ncbi.nlm.nih.gov/pubmed/30463319
http://dx.doi.org/10.3390/ijms19113664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274715/
https://www.ncbi.nlm.nih.gov/pubmed/30463319
http://dx.doi.org/10.3390/ijms19113664

Ejemplares similares