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Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases

Structural and functional studies have provided numerous insights over the past years on how members of the nuclear hormone receptor superfamily tightly regulate the expression of drug-metabolizing enzymes and transporters. Besides the role of the farnesoid X receptor (FXR) in the transcriptional co...

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Detalles Bibliográficos
Autores principales: Garcia, Manon, Thirouard, Laura, Sedès, Lauriane, Monrose, Mélusine, Holota, Hélène, Caira, Françoise, Volle, David H., Beaudoin, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274770/
https://www.ncbi.nlm.nih.gov/pubmed/30453651
http://dx.doi.org/10.3390/ijms19113630