Role of Overexpressed Transcription Factor FOXO1 in Fatal Cardiovascular Septal Defects in Patau Syndrome: Molecular and Therapeutic Strategies

Patau Syndrome (PS), characterized as a lethal disease, allows less than 15% survival over the first year of life. Most deaths owe to brain and heart disorders, more so due to septal defects because of altered gene regulations. We ascertained the cytogenetic basis of PS first, followed by molecular...

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Detalles Bibliográficos
Autores principales: Abuzenadah, Adel, Alsaedi, Saad, Karim, Sajjad, Al-Qahtani, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274780/
https://www.ncbi.nlm.nih.gov/pubmed/30423812
http://dx.doi.org/10.3390/ijms19113547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274780/
https://www.ncbi.nlm.nih.gov/pubmed/30423812
http://dx.doi.org/10.3390/ijms19113547

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