Molecular Docking, Computational, and Antithrombotic Studies of Novel 1,3,4-Oxadiazole Derivatives

A new series of 1,3,4-oxadiazoles derivatives was synthesized, characterized, and evaluated for their in vitro and in vivo anti-thrombotic activity. Compounds (3a–3i) exhibited significant clot lysis with respect to reference drug streptokinase (30,000 IU), and enhanced clotting time (CT) values (13...

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Detalles Bibliográficos
Autores principales: Batool, Majda, Tajammal, Affifa, Farhat, Firdous, Verpoort, Francis, Khattak, Zafar A. K., Mehr-un-Nisa, Shahid, Muhammad, Ahmad, Hafiz Adnan, Munawar, Munawar Ali, Zia-ur-Rehman, Muhammad, Asim Raza Basra, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274789/
https://www.ncbi.nlm.nih.gov/pubmed/30445728
http://dx.doi.org/10.3390/ijms19113606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274789/
https://www.ncbi.nlm.nih.gov/pubmed/30445728
http://dx.doi.org/10.3390/ijms19113606

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