Discovery of Heterotopic Bone-Inducing Activity in Hard Tissues and the TGF-β Superfamily

Bone is a unique organ because it can be experimentally induced in soft tissues by implanting a single growth factor, bone morphogenetic protein (BMP). Heterotopic bone-inducing activity was found in demineralized bone matrix in 1965. The characterization of this activity in bone enabled the purific...

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Detalles Bibliográficos
Autores principales: Katagiri, Takenobu, Tsukamoto, Sho, Nakachi, Yutaka, Kuratani, Mai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274805/
https://www.ncbi.nlm.nih.gov/pubmed/30428615
http://dx.doi.org/10.3390/ijms19113586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274805/
https://www.ncbi.nlm.nih.gov/pubmed/30428615
http://dx.doi.org/10.3390/ijms19113586

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