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Discovery of Heterotopic Bone-Inducing Activity in Hard Tissues and the TGF-β Superfamily
Bone is a unique organ because it can be experimentally induced in soft tissues by implanting a single growth factor, bone morphogenetic protein (BMP). Heterotopic bone-inducing activity was found in demineralized bone matrix in 1965. The characterization of this activity in bone enabled the purific...
Autores principales: | Katagiri, Takenobu, Tsukamoto, Sho, Nakachi, Yutaka, Kuratani, Mai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274805/ https://www.ncbi.nlm.nih.gov/pubmed/30428615 http://dx.doi.org/10.3390/ijms19113586 |
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