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DNA Vaccines—How Far From Clinical Use?

Two decades ago successful transfection of antigen presenting cells (APC) in vivo was demonstrated which resulted in the induction of primary adaptive immune responses. Due to the good biocompatibility of plasmid DNA, their cost-efficient production and long shelf life, many researchers aimed to dev...

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Detalles Bibliográficos
Autores principales: Hobernik, Dominika, Bros, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274812/
https://www.ncbi.nlm.nih.gov/pubmed/30445702
http://dx.doi.org/10.3390/ijms19113605