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Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL12

Upon binding with the chemokine CXCL12, the chemokine receptor CXCR4 has been shown to promote breast cancer progression. This process, however, can be affected by the expression of the atypical chemokine receptor ACKR3. Given ACKR3’s ability to form heterodimers with CXCR4, we investigated how dual...

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Detalles Bibliográficos
Autores principales: del Molino del Barrio, Irene, Wilkins, Georgina C., Meeson, Annette, Ali, Simi, Kirby, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274818/
https://www.ncbi.nlm.nih.gov/pubmed/30441765
http://dx.doi.org/10.3390/ijms19113592