Interactions Between Spermine-Derivatized Tentacle Porphyrins and The Human Telomeric DNA G-Quadruplex

G-rich DNA sequences have the potential to fold into non-canonical G-Quadruplex (GQ) structures implicated in aging and human diseases, notably cancers. Because stabilization of GQs at telomeres and oncogene promoters may prevent cancer, there is an interest in developing small molecules that select...

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Detalles Bibliográficos
Autores principales: Sabharwal, Navin C., Chen, Jessica, Lee, Joo Hyun (June), Gangemi, Chiara M. A., D’Urso, Alessandro, Yatsunyk, Liliya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274827/
https://www.ncbi.nlm.nih.gov/pubmed/30469358
http://dx.doi.org/10.3390/ijms19113686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274827/
https://www.ncbi.nlm.nih.gov/pubmed/30469358
http://dx.doi.org/10.3390/ijms19113686

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