T-2 Toxin Exposure Induces Apoptosis in TM3 Cells by Inhibiting Mammalian Target of Rapamycin/Serine/Threonine Protein Kinase(mTORC2/AKT) to Promote Ca(2+)Production

Although mTOR (the mammalian target of rapamycin) can regulate intracellular free Ca(2+)concentration in normal cultured podocytes, it remains elusive as to how mTORC2/AKT-mediated Ca(2+)participates in the process of T-2 toxin-induced apoptosis. The potential signaling responsible for intracellular...

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Detalles Bibliográficos
Autores principales: Wang, Ji, Yang, Chenglin, Yuan, Zhihang, Yi, Jine, Wu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274855/
https://www.ncbi.nlm.nih.gov/pubmed/30373220
http://dx.doi.org/10.3390/ijms19113360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274855/
https://www.ncbi.nlm.nih.gov/pubmed/30373220
http://dx.doi.org/10.3390/ijms19113360

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