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T-2 Toxin Exposure Induces Apoptosis in TM3 Cells by Inhibiting Mammalian Target of Rapamycin/Serine/Threonine Protein Kinase(mTORC2/AKT) to Promote Ca(2+)Production
Although mTOR (the mammalian target of rapamycin) can regulate intracellular free Ca(2+)concentration in normal cultured podocytes, it remains elusive as to how mTORC2/AKT-mediated Ca(2+)participates in the process of T-2 toxin-induced apoptosis. The potential signaling responsible for intracellular...
Autores principales: | Wang, Ji, Yang, Chenglin, Yuan, Zhihang, Yi, Jine, Wu, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274855/ https://www.ncbi.nlm.nih.gov/pubmed/30373220 http://dx.doi.org/10.3390/ijms19113360 |
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