The 2β Splice Variation Alters the Structure and Function of the Stromal Interaction Molecule Coiled-Coil Domains

Stromal interaction molecule (STIM)-1 and -2 regulate agonist-induced and basal cytosolic calcium (Ca(2+)) levels after oligomerization and translocation to endoplasmic reticulum (ER)-plasma membrane (PM) junctions. At these junctions, the STIM cytosolic coiled-coil (CC) domains couple to PM Orai1 p...

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Detalles Bibliográficos
Autores principales: Chung, Steve, Zhang, MengQi, Stathopulos, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274866/
https://www.ncbi.nlm.nih.gov/pubmed/30366379
http://dx.doi.org/10.3390/ijms19113316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274866/
https://www.ncbi.nlm.nih.gov/pubmed/30366379
http://dx.doi.org/10.3390/ijms19113316

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