Hierarchical Clustering of DNA k-mer Counts in RNAseq Fastq Files Identifies Sample Heterogeneities

We apply hierarchical clustering (HC) of DNA k-mer counts on multiple Fastq files. The tree structures produced by HC may reflect experimental groups and thereby indicate experimental effects, but clustering of preparation groups indicates the presence of batch effects. Hence, HC of DNA k-mer counts...

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Detalles Bibliográficos
Autores principales: Kaisers , Wolfgang, Schwender, Holger, Schaal , Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274891/
https://www.ncbi.nlm.nih.gov/pubmed/30469355
http://dx.doi.org/10.3390/ijms19113687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274891/
https://www.ncbi.nlm.nih.gov/pubmed/30469355
http://dx.doi.org/10.3390/ijms19113687

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