Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and C. elegans

Sirtuin 1 (SIRT1) othologs are ubiquitous NAD(+)-dependent deacetylases that act as nutrient sensors and modulate metabolism and stress responses in diverse organisms. Both mammalian SIRT1 and Caenorhabditis elegans SIR-2.1 have been implicated in dietary restriction, longevity, and healthspan. Hsp9...

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Detalles Bibliográficos
Autores principales: Nguyen, Minh Tu, Somogyvári, Milán, Sőti, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930/
https://www.ncbi.nlm.nih.gov/pubmed/30463299
http://dx.doi.org/10.3390/ijms19113661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930/
https://www.ncbi.nlm.nih.gov/pubmed/30463299
http://dx.doi.org/10.3390/ijms19113661

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