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Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and C. elegans
Sirtuin 1 (SIRT1) othologs are ubiquitous NAD(+)-dependent deacetylases that act as nutrient sensors and modulate metabolism and stress responses in diverse organisms. Both mammalian SIRT1 and Caenorhabditis elegans SIR-2.1 have been implicated in dietary restriction, longevity, and healthspan. Hsp9...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930/ https://www.ncbi.nlm.nih.gov/pubmed/30463299 http://dx.doi.org/10.3390/ijms19113661 |