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Toxicity Evaluation and Biomarker Selection with Validated Reference Gene in Embryonic Zebrafish Exposed to Mitoxantrone

Notwithstanding the widespread use and promising clinical value of chemotherapy, the pharmacokinetics, toxicology, and mechanism of mitoxantrone remains unclear. To promote the clinical value in the treatment of human diseases and the exploration of potential subtle effects of mitoxantrone, zebrafis...

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Detalles Bibliográficos
Autores principales: Liu, Lili, Zhu, Hua, Yan, Yanchun, Lv, Peng, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274943/
https://www.ncbi.nlm.nih.gov/pubmed/30413070
http://dx.doi.org/10.3390/ijms19113516