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The Protective Role of Dormant Origins in Response to Replicative Stress

Genome stability requires tight regulation of DNA replication to ensure that the entire genome of the cell is duplicated once and only once per cell cycle. In mammalian cells, origin activation is controlled in space and time by a cell-specific and robust program called replication timing. About 100...

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Detalles Bibliográficos
Autores principales: Courtot, Lilas, Hoffmann, Jean-Sébastien, Bergoglio, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274952/
https://www.ncbi.nlm.nih.gov/pubmed/30424570
http://dx.doi.org/10.3390/ijms19113569