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Sub-Toxic Human Amylin Fragment Concentrations Promote the Survival and Proliferation of SH-SY5Y Cells via the Release of VEGF and HspB5 from Endothelial RBE4 Cells

Human amylin is a 37-residue peptide hormone (hA1-37) secreted by β-cells of the pancreas and, along with insulin, is directly associated with type 2 diabetes mellitus (T2DM). Amyloid deposits within the islets of the pancreas represent a hallmark of T2DM. Additionally, amylin aggregates have been f...

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Detalles Bibliográficos
Autores principales: Caruso, Giuseppe, Fresta, Claudia G., Lazzarino, Giacomo, Distefano, Donatella A., Parlascino, Paolo, Lunte, Susan M., Lazzarino, Giuseppe, Caraci, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274958/
https://www.ncbi.nlm.nih.gov/pubmed/30463298
http://dx.doi.org/10.3390/ijms19113659