Endothelial Microsomal Prostaglandin E Synthetase-1 Upregulates Vascularity and Endothelial Interleukin-1β in Deteriorative Progression of Experimental Autoimmune Encephalomyelitis

Microsomal prostaglandin E synthetase-1 (mPGES-1) is an inducible terminal enzyme for the production of prostaglandin E(2) (PGE(2)). In experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis, mPGES-1 is induced in vascular endothelial cells (VECs) around inflammatory...

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Detalles Bibliográficos
Autores principales: Takemiya, Takako, Kawakami, Marumi, Takeuchi, Chisen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274996/
https://www.ncbi.nlm.nih.gov/pubmed/30463256
http://dx.doi.org/10.3390/ijms19113647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274996/
https://www.ncbi.nlm.nih.gov/pubmed/30463256
http://dx.doi.org/10.3390/ijms19113647

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