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The Pub1 and Upf1 Proteins Act in Concert to Protect Yeast from Toxicity of the [PSI(+)] Prion

The [PSI(+)] nonsense-suppressor determinant of Saccharomyces cerevisiae is based on the formation of heritable amyloids of the Sup35 (eRF3) translation termination factor. [PSI(+)] amyloids have variants differing in amyloid structure and in the strength of the suppressor phenotype. The appearance...

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Detalles Bibliográficos
Autores principales: Urakov, Valery N., Mitkevich, Olga V., Dergalev, Alexander A., Ter-Avanesyan, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275000/
https://www.ncbi.nlm.nih.gov/pubmed/30463309
http://dx.doi.org/10.3390/ijms19113663