BCPA {N,N′-1,4-Butanediylbis[3-(2-chlorophenyl)acrylamide]} Inhibits Osteoclast Differentiation through Increased Retention of Peptidyl-Prolyl cis-trans Isomerase Never in Mitosis A-Interacting 1

Osteoporosis is caused by an imbalance of osteoclast and osteoblast activities and it is characterized by enhanced osteoclast formation and function. Peptidyl-prolyl cis-trans isomerase never in mitosis A (NIMA)-interacting 1 (Pin1) is a key mediator of osteoclast cell-cell fusion via suppression of...

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, Eugene, Lee, Jin-Kyung, Lee, Jee-Young, Chen, Zhihao, Ahn, Sun-Hee, Kim, Nam Doo, Kook, Min-Suk, Min, Sang Hyun, Park, Byung-Ju, Lee, Tae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275020/
https://www.ncbi.nlm.nih.gov/pubmed/30388885
http://dx.doi.org/10.3390/ijms19113436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275020/
https://www.ncbi.nlm.nih.gov/pubmed/30388885
http://dx.doi.org/10.3390/ijms19113436

Ejemplares similares