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The Bromodomain Inhibitor N-Methyl pyrrolidone Prevents Osteoporosis and BMP-Triggered Sclerostin Expression in Osteocytes

(1) Background: In an adult skeleton, bone is constantly renewed in a cycle of bone resorption, followed by bone formation. This coupling process, called bone remodeling, adjusts the quality and quantity of bone to the local needs. It is generally accepted that osteoporosis develops when bone resorp...

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Detalles Bibliográficos
Autores principales: Siegenthaler, Barbara, Ghayor, Chafik, Gjoksi-Cosandey, Bebeka, Ruangsawasdi, Nisarat, Weber, Franz E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275050/
https://www.ncbi.nlm.nih.gov/pubmed/30366476
http://dx.doi.org/10.3390/ijms19113332