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Atomistic Analysis of ToxN and ToxI Complex Unbinding Mechanism

ToxIN is a triangular structure formed by three protein toxins (ToxNs) and three specific noncoding RNA antitoxins (ToxIs). To respond to stimuli, ToxI is preferentially degraded, releasing the ToxN. Thus, the dynamic character is essential in the normal function interactions between ToxN and ToxI....

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Detalles Bibliográficos
Autores principales: Hu, Guodong, Yu, Xiu, Bian, Yunqiang, Cao, Zanxia, Xu, Shicai, Zhao, Liling, Ji, Baohua, Wang, Wei, Wang, Jihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275071/
https://www.ncbi.nlm.nih.gov/pubmed/30423909
http://dx.doi.org/10.3390/ijms19113524