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Methyl-β-Cyclodextrin Impairs the Phosphorylation of the β(2) Subunit of L-Type Calcium Channels and Cytosolic Calcium Homeostasis in Mature Cerebellar Granule Neurons

The activation of L-type calcium channels (LTCCs) prevents cerebellar granule neurons (CGNs) from entering low-K(+)-induced apoptosis. In previous works, we showed that LTCCs are largely associated with caveolin-1-rich lipid rafts in the CGN plasma membrane. In this work, we show that protein kinase...

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Detalles Bibliográficos
Autores principales: Fortalezas, Sofia, Marques-da-Silva, Dorinda, Gutierrez-Merino, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275079/
https://www.ncbi.nlm.nih.gov/pubmed/30463327
http://dx.doi.org/10.3390/ijms19113667