Cargando…

Artificial Activation of Escherichia coli mazEF and hipBA Toxin–Antitoxin Systems by Antisense Peptide Nucleic Acids as an Antibacterial Strategy

The search for new, non-standard targets is currently a high priority in the design of new antibacterial compounds. Bacterial toxin–antitoxin systems (TAs) are genetic modules that encode a toxin protein that causes growth arrest by interfering with essential cellular processes, and a cognate antito...

Descripción completa

Detalles Bibliográficos
Autores principales: Równicki, Marcin, Pieńko, Tomasz, Czarnecki, Jakub, Kolanowska, Monika, Bartosik, Dariusz, Trylska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275173/
https://www.ncbi.nlm.nih.gov/pubmed/30534121
http://dx.doi.org/10.3389/fmicb.2018.02870