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Artificial Activation of Escherichia coli mazEF and hipBA Toxin–Antitoxin Systems by Antisense Peptide Nucleic Acids as an Antibacterial Strategy
The search for new, non-standard targets is currently a high priority in the design of new antibacterial compounds. Bacterial toxin–antitoxin systems (TAs) are genetic modules that encode a toxin protein that causes growth arrest by interfering with essential cellular processes, and a cognate antito...
Autores principales: | Równicki, Marcin, Pieńko, Tomasz, Czarnecki, Jakub, Kolanowska, Monika, Bartosik, Dariusz, Trylska, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275173/ https://www.ncbi.nlm.nih.gov/pubmed/30534121 http://dx.doi.org/10.3389/fmicb.2018.02870 |
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