Renal Cell Carcinoma (RCC) Tumors Display Large Expansion of Double Positive (DP) CD4+CD8+ T Cells With Expression of Exhaustion Markers

Checkpoint inhibitors target the inhibitory receptors expressed by tumor-infiltrating T cells in order to reinvigorate an anti-tumor immune response. Therefore, understanding T cell composition and phenotype in human tumors is crucial. We analyzed by flow cytometry tumor-infiltrating lymphocytes (TI...

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Detalles Bibliográficos
Autores principales: Menard, Laurence C., Fischer, Paul, Kakrecha, Bijal, Linsley, Peter S., Wambre, Erik, Liu, Maochang C., Rust, Blake J., Lee, Deborah, Penhallow, Becky, Manjarrez Orduno, Nataly, Nadler, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275222/
https://www.ncbi.nlm.nih.gov/pubmed/30534127
http://dx.doi.org/10.3389/fimmu.2018.02728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275222/
https://www.ncbi.nlm.nih.gov/pubmed/30534127
http://dx.doi.org/10.3389/fimmu.2018.02728

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