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Trastuzumab induces PUMA‐dependent apoptosis and inhibits tumor growth in gastric cancer

Gastric cancer (GC) is one of the most prevalent cancers worldwide. Trastuzumab has been approved for the treatment of metastatic GC, gastroesophageal junction cancer, and breast cancer. However, the mechanisms involved in trastuzumab‐induced GC cell apoptosis remain largely unknown. In this study,...

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Detalles Bibliográficos
Autores principales: Luo, Linghe, Liu, Haiyan, Xi, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275257/
https://www.ncbi.nlm.nih.gov/pubmed/30524942
http://dx.doi.org/10.1002/2211-5463.12522