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Role of TGF‐β1/miR‐382‐5p/SOD2 axis in the induction of oxidative stress in CD34+ cells from primary myelofibrosis

Primary myelofibrosis (PMF) is a myeloproliferative neoplasm characterized by an excessive production of pro‐inflammatory cytokines resulting in chronic inflammation and genomic instability. Besides the driver mutations in JAK2,MPL, and CALR genes, the deregulation of miRNA expression may also contr...

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Detalles Bibliográficos
Autores principales: Rossi, Chiara, Zini, Roberta, Rontauroli, Sebastiano, Ruberti, Samantha, Prudente, Zelia, Barbieri, Greta, Bianchi, Elisa, Salati, Simona, Genovese, Elena, Bartalucci, Niccolò, Guglielmelli, Paola, Tagliafico, Enrico, Rosti, Vittorio, Barosi, Giovanni, Vannucchi, Alessandro M., Manfredini, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275274/
https://www.ncbi.nlm.nih.gov/pubmed/30259659
http://dx.doi.org/10.1002/1878-0261.12387