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Efficacy of nano‐particulated, water‐soluble erlotinib against intracranial metastases of EGFR‐mutant lung cancer

Central nervous system (CNS) metastasis is one of the serious complications of epidermal growth factor receptor (EGFR)‐mutant lung cancer, which arises due to poor penetration of the brain–blood barrier by EGFR‐tyrosine kinase inhibitors (EGFR‐TKIs). Although osimertinib, a third‐generation EGFR‐TKI...

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Detalles Bibliográficos
Autores principales: Kim, Dong Ha, Choi, Yun Jung, Sung, Ki Jung, Yoo, Seon‐A, Sung, Young Hoon, Kim, Jeong Kon, Choi, Chang‐Min, Yun, Miyong, Lee, Eun Yong, Jin, Yong Suk, Cook, Seungho, Rho, Jin Kyung, Lee, Jae Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275278/
https://www.ncbi.nlm.nih.gov/pubmed/30350450
http://dx.doi.org/10.1002/1878-0261.12394