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Chemo-Radiotherapy of Oligometastases of Colorectal Cancer With Pegylated Liposomal Mitomycin-C Prodrug (Promitil): Mechanistic Basis and Preliminary Clinical Experience

Hypo-fractionated radiotherapy and stereotactic body radiotherapy are viable options for treatment of oligometastases. A prodrug of mitomycin-C is under clinical testing as a pegylated liposomal formulation (Promitil) with an improved safety profile over mitomycin-C. Promitil was offered to two pati...

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Detalles Bibliográficos
Autores principales: Tahover, Esther, Bar-Shalom, Rachel, Sapir, Eli, Pfeffer, Raphael, Nemirovsky, Igor, Turner, Yehonatan, Gips, Maya, Ohana, Patricia, Corn, Benjamin W., Wang, Andrew Z., Gabizon, Alberto A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275313/
https://www.ncbi.nlm.nih.gov/pubmed/30534533
http://dx.doi.org/10.3389/fonc.2018.00544