Themis-associated phosphatase activity controls signaling in T cell development

Thymocyte-expressed molecule involved in selection (Themis) has been shown to be important for T cell selection by setting the threshold for positive versus negative selection. Themis interacts with the protein tyrosine phosphatase (PTP) Src-homology domain containing phosphatase-1 (Shp1), a negativ...

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Detalles Bibliográficos
Autores principales: Mehta, Monika, Brzostek, Joanna, Chen, Elijah W., Tung, Desmond W. H., Chen, Shuting, Sankaran, Shvetha, Yap, Jiawei, Rybakin, Vasily, Gascoigne, Nicholas R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275480/
https://www.ncbi.nlm.nih.gov/pubmed/30413615
http://dx.doi.org/10.1073/pnas.1720209115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275480/
https://www.ncbi.nlm.nih.gov/pubmed/30413615
http://dx.doi.org/10.1073/pnas.1720209115

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