Multiple prebiotic metals mediate translation

Today, Mg(2+) is an essential cofactor with diverse structural and functional roles in life’s oldest macromolecular machine, the translation system. We tested whether ancient Earth conditions (low O(2), high Fe(2+), and high Mn(2+)) can revert the ribosome to a functional ancestral state. First, SHA...

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Detalles Bibliográficos
Autores principales: Bray, Marcus S., Lenz, Timothy K., Haynes, Jay William, Bowman, Jessica C., Petrov, Anton S., Reddi, Amit R., Hud, Nicholas V., Williams, Loren Dean, Glass, Jennifer B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275528/
https://www.ncbi.nlm.nih.gov/pubmed/30413624
http://dx.doi.org/10.1073/pnas.1803636115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275528/
https://www.ncbi.nlm.nih.gov/pubmed/30413624
http://dx.doi.org/10.1073/pnas.1803636115

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