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Multiple prebiotic metals mediate translation
Today, Mg(2+) is an essential cofactor with diverse structural and functional roles in life’s oldest macromolecular machine, the translation system. We tested whether ancient Earth conditions (low O(2), high Fe(2+), and high Mn(2+)) can revert the ribosome to a functional ancestral state. First, SHA...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275528/ https://www.ncbi.nlm.nih.gov/pubmed/30413624 http://dx.doi.org/10.1073/pnas.1803636115 |