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Klotho controls the brain–immune system interface in the choroid plexus

Located within the brain’s ventricles, the choroid plexus produces cerebrospinal fluid and forms an important barrier between the central nervous system and the blood. For unknown reasons, the choroid plexus produces high levels of the protein klotho. Here, we show that these levels naturally declin...

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Detalles Bibliográficos
Autores principales: Zhu, Lei, Stein, Liana R., Kim, Daniel, Ho, Kaitlyn, Yu, Gui-Qiu, Zhan, Lihong, Larsson, Tobias E., Mucke, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275534/
https://www.ncbi.nlm.nih.gov/pubmed/30413620
http://dx.doi.org/10.1073/pnas.1808609115