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Klotho controls the brain–immune system interface in the choroid plexus
Located within the brain’s ventricles, the choroid plexus produces cerebrospinal fluid and forms an important barrier between the central nervous system and the blood. For unknown reasons, the choroid plexus produces high levels of the protein klotho. Here, we show that these levels naturally declin...
Autores principales: | Zhu, Lei, Stein, Liana R., Kim, Daniel, Ho, Kaitlyn, Yu, Gui-Qiu, Zhan, Lihong, Larsson, Tobias E., Mucke, Lennart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275534/ https://www.ncbi.nlm.nih.gov/pubmed/30413620 http://dx.doi.org/10.1073/pnas.1808609115 |
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