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Stress-induced expression of p53 target genes is insensitive to SNW1/SKIP downregulation

Pharmacological inhibition of protein kinases that are responsible for the phosphorylation of the carboxy-terminal domain (CTD) of RNA Pol II during transcription by 5,6-dichloro-1-beta-D-ribofuranosyl-benzimidazole (DRB) leads to severe inhibition of mRNA synthesis and activates p53. Transcription...

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Detalles Bibliográficos
Autores principales: Tolde, Ondřej, Folk, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275595/
https://www.ncbi.nlm.nih.gov/pubmed/21461980
http://dx.doi.org/10.2478/s11658-011-0012-1