The influence of JNK and P38 MAPK inhibition on IL-12P40 and IL-23 production depending on IL12B promoter polymorphism

The interleukin-12p40 gene (IL12B) encodes the p40 polypeptide chain, which, together with p19, composes IL-23. A bi-allelic promoter polymorphism (IL12Bpro) located at −2703 bp of the transcription initiation site has been reported to show associations with IL-12p40 production. To elucidate the dep...

Descripción completa

Detalles Bibliográficos
Autores principales: Dobreva, Zlatka Georgieva, Stanilova, Spaska Angelova, Miteva, Lyuba Dineva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2009
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275601/
https://www.ncbi.nlm.nih.gov/pubmed/19554267
http://dx.doi.org/10.2478/s11658-009-0022-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275601/
https://www.ncbi.nlm.nih.gov/pubmed/19554267
http://dx.doi.org/10.2478/s11658-009-0022-4

Ejemplares similares